In a mixing bowl, combine cubed chicken breast with BBQ sauce, olive oil, garlic powder, onion powder, salt, and black pepper. Ensure each piece is well-coated for maximum flavor absorption. Cover and refrigerate for at least 30 minutes; for best results, marinate overnight.

Preheat your grill to medium-high, roughly 375°F (190°C). If using wooden skewers, soak them in water for about 30 minutes to prevent burning on the grill.

After marinating, thread the marinated chicken cubes onto your skewers, leaving a little space between them for even cooking. Add vegetables if desired.

Carefully place the skewers on the preheated grill and cook for about 15 minutes, turning occasionally to ensure even charring.

Once grilled to perfection, remove the BBQ Chicken Skewers from the grill and allow them to rest for a few minutes before serving.